Metal ion induced allosteric transition in the catalytic activity of an artificial phosphodiesterase.

نویسندگان

  • Shinji Takebayashi
  • Masato Ikeda
  • Masayuki Takeuchi
  • Seiji Shinkai
چکیده

An artificial phosphodiesterase (1) bearing two kinds of metal binding sites, a catalytic site and a regulatory bipyridine site showed a unique allosteric transition in the catalytic activity against the metal concentration.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Synthesis and Metal Ion Uptake Studies of Silica Gel-Immobilized Schiff Base Derivatives and Catalytic Behaviors of their Cu(II) Complexes

New silica supported Schiff base ligands were prepared by the condensation reaction of 4,6-diacetylresorcinol with silica-gel derivatives, which modified with 3-aminopropyltriethoxysilane and N-(2-aminoethyl) -3-aminopropyltrimethoxysilane. Metal ion uptake capacities of these compounds were studied towards of selected transition metal (Cd(II), Cu(II), Co(II), Mn(II), Pb(II) and Ni(II)) cations...

متن کامل

A comparative study between transition-metal-substituted Keggin-type tungstosilicates supported on anatase leaf as catalyst for synthesis of symmetrical disulfides

Transition-metal-substituted  (TMS)  polyoxometalates  of  the  general  formula  [SiW9M3O39], (where M = first row transition metal), has been synthesized and supported on anatase by sol–gel method under oil-bath condition. The tetrabutylammonium (TBA) salts of the Keggin-type polyoxotungstates  [SiW9M3O39],  (M = VII, CrII, MnII,  FeII CoII  and NiII),  proved  to  be  green, reusable,  and  ...

متن کامل

STUDY ON THE COMPLEX FORMATION BETWEEN N-PROPYLSALICYLIDENE BASED ON SILICA AS ION EXCHANGER AND SOME TRANSITION METAL IONS

N-propylsalicylidene based on silica as ion exchanger (IE) was used for the separation by complexation of Mn2+, Co2+, Ni2+, Cu2+, Hg2+, Cr3+, Fe3+, and UO22+ from their parent solutions. IE and its metal complexes are characterized by elemental analysis, electronic and infrared spectra, in addition to thermal analysis in atmospheric pressure. The mode of chelation and the proposed geometric str...

متن کامل

Zinc as Allosteric Ion Channel Modulator: Ionotropic Receptors as Metalloproteins

Zinc is an essential metal to life. This transition metal is a structural component of many proteins and is actively involved in the catalytic activity of cell enzymes. In either case, these zinc-containing proteins are metalloproteins. However, the amino acid residues that serve as ligands for metal coordination are not necessarily the same in structural proteins compared to enzymes. While cry...

متن کامل

Tailoring the Energy Band Gap of Transition Metal Doped TiO2 Thin Film

Water splitting for hydrogen production under sunlight using TiO2 as photo catalyst provides a better route for solar energy and attracts the attention of many researchers. The photo catalytic activity of TiO2 under sunlight irradiation depends on the band gap energy. The transition metal doped TiO2 shows an edge over TiO2 in optical absorbance and photo catalytic activity. Thin film of Cr dope...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Chemical communications

دوره 4  شماره 

صفحات  -

تاریخ انتشار 2004